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Community based malaria testing reduces polypharmacy in a population based survey of febrile illness in Western Kenya

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dc.contributor.author Laktabai, Jeremiah
dc.contributor.author C. Platt, Alyssa
dc.contributor.author Turner, Elizabeth
dc.contributor.author Saran, Indrani
dc.contributor.author Kipkoech, Joseph
dc.contributor.author Menya, Diana
dc.contributor.author Prudhomme O’Meara, Wendy
dc.date.accessioned 2022-11-11T08:05:47Z
dc.date.available 2022-11-11T08:05:47Z
dc.date.issued 2022-08-25
dc.identifier.uri https://doi.org/10.3389/ijph.2022.1604826
dc.identifier.uri http://ir.mu.ac.ke:8080/jspui/handle/123456789/7062
dc.description.abstract Objective: The objective was to describe the relationship between the location of care, the malaria test result, and the type of medicine consumed for the fever, and to determine whether community-based access to malaria testing reduced polypharmacy. Methods: This is a secondary analysis of a cluster-randomized trial of an intervention designed to increase diagnostic testing and targeting of Artemesinin Combined Therapies (ACTs). Data collected at baseline, 12, and 18 months were analyzed to determine the impact of diagnostic testing on drug consumption patterns among febrile individuals. Results: Of the 5,756 participants analyzed, 60.1% were female, 42% were aged 5–17 years, and 58.1% sought care for fever in a retail outlet. Consumption of both ACT and antibiotics was 22.1% (n = 443/2008) at baseline. At endline, dual consumption had declined to 16.6%. There was reduced antibiotic consumption among those testing positive for malaria (39.5%–26.5%) and those testing negative (63.4%–55.1%), accompanied by a substantial decline in ACT use among malaria-negative participants. Conclusion: Diagnostic testing for malaria reduces dual consumption of ACTs and antibiotics, especially among those testing outside the formal healthcare sector en_US
dc.description.sponsorship R01AI110478 en_US
dc.language.iso en en_US
dc.publisher Frontiers en_US
dc.subject Antibiotics en_US
dc.subject Antimalarial en_US
dc.subject Antimalarials en_US
dc.subject Fever en_US
dc.subject Polypharmacy en_US
dc.subject Malaria testing en_US
dc.title Community based malaria testing reduces polypharmacy in a population based survey of febrile illness in Western Kenya en_US
dc.type Article en_US


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