Browsing School of Public Health by Author "Dzamalala, Charles P."

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Genome-wide DNA methylation profiling of esophageal squamous cell carcinoma from global high-incidence regions identifies crucial genes and potential

Boisson, Anne-Claire; Abedi-Ardekani, Behnoush; Carreira, Christine; Menya, Diana; Dzamalala, Charles P.; Assefa, Mathewos; Aseffa, Abraham (AACR, 2021)

Epigenetic mechanisms such as aberrant DNA methylation (DNAme) are known to drive esophageal squamous cell carcinoma (ESCC), yet they remain poorly understood. Here, we studied tumor-specific DNAme in ESCC cases from nine ...
Geophagia and risk of squamous cell esophageal cancer in the African esophageal cancer corridor: Findings from the ESCCAPE multicountry case-control studies

Narh, Clement T.; Dzamalala, Charles P.; Mmbaga, Blandina T.; Menya, Diana; Mlombe, Yohannie; Finch, Peter; Nyakunga, Gissela (Wiley online library, 2021-05-04)

Geophagia, the intentional practice of consuming soil, occurs across the African esopha- geal cancer corridor, particularly during pregnancy. We investigated whether this practice is linked to endemic esophageal squamous ...

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