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Browsing Research Publications by Subject "Cancer"

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Access to essential cancer medicines for children: A comparative mixed-methods analysis of availability, price, and health-system determinants in East Africa

kambugu, Joyce (Lancet, 2023)

Background Access to essential childhood cancer medicines is a core determinant of childhood cancer outcomes. Available evidence, although scarce, suggests that access to these medicines is highly variable across countries, ...
Accuracy of Clinical suspicion and pathologic diagnosis of Kaposi Sarcoma in East Africa

Laker-Okett, Miriam; Muyindike, Winnie; Busakhala, Naftali (Clinical science, 2016)

Background: HIV-associated Kaposi sarcoma (KS) is one of the most common malignancies in sub-Saharan Africa. The diagnosis is often based on clinical suspicion, without histopathologic con fi rmation. When biopsies ...
Bacterial isolates and characteristics of children With febrile Neutropenia on treatment for cancer at a Tertiary Hospital in Western Kenya

Kipchumba, Samuel Kipkemoi; Njuguna's, Festus Muigai; Nyandiko, Winstone Mokaya (JCO Global Oncology, 2024-02)

URPOSE This study aimed to identify the patient characteristics of children with febrile neutropenia, the associated bacterial organisms, and their sensitivity patterns. MATERIALS AND METHODS A descriptive cross-sectional ...
Building cancer nursing skills in a resource-constrained government hospital

Strother, R.M.; Fitch, Margaret; Kamau, Peter; Beattie, Kathy; Boudreau, Angela; Busakhalla, N.; Loehrer, P. J. (Springer, 2012)

Cancer is a rising cause of morbidity and mortality in resource-constrained settings. Few places in the developing world have cancer care experts and infrastructure for caring for cancer patients; therefore, it is imperative ...
Cancer progression is associated with increased expression of basement membrane proteins in three-dimensional in vitro models of human oral cancer

Kulasekara Keerthi K.; Lukandu Ochiba M.; Neppelberg Evelyn; Vintermyr Olav K.; Johannessen Anne Christine; Costea Daniela Elena (Elsevier, 2009-07-18)

Background: Although basement membrane was traditionally considered an inert barrier that tumour cells had to cross before invasion into the surrounding stroma, recent studies suggest that basement membrane components ...
Demographic characteristics, presentation, risk factors and treatment of patients with squamous cell carcinoma of the penis at Moi Teaching and Referral Hospital Eldoret, Kenya

Mugalo, E. L. (AJOL, 2021-06-06)

Background: Squamous cell carcinoma (SCC)of the penis is a rare cancer that affects mainly elderly men. Presence of fore skin in the uncircumcised, Human Papilloma Virus (HPV) infection, tobacco smoking and Human Immune ...
Dental fluorosis and oral health in the African Esophageal Cancer Corridor: Findings from the Kenya ESCCAPE case–control study and a pan‐African perspective

Menya Diana; Stephen K.Maina; Kibosia Caroline; Kigen Nicholas; Oduor Margaret; Fatma Some; Chumba David; Ayuo Paul; Odipo Osano (Wiley Online Library, 2018-12)
Development of a national cancer registry in a low resourced country: The case of Kenya National Cancer Registry Programme

Korir, Anne; Gakunga, Robai; Okerosi, Nathan (Global oncology, 2018)

Background: Population-based cancer registration represents the gold standard for the provision of information on cancer incidence in a defined population (Bray F, et. al, IARC Technical Report No. 43). In Kenya, the ...
Development of a National Cancer Registry in a low resourced country: The case of Kenya National Cancer Registry Programme

Korir, Anne; Gakunga, Robai; Okerosi, Nathan; Karagu, Alfred (ASCO, 2018)

Background: Population-based cancer registration represents the gold standard for the provision of information on cancer incidence in a defined population (Bray F, et. al, IARC Technical Report No. 43). In Kenya, the ...
Development of immunohistochemistry services for cancer care in western Kenya: Implications for low- and middle-income countries

Ndiangui, Francis; Chumba, David; Kirtika, Patel (AJLM, 2016)

Background: Cancer is becoming a major cause of mortality in low- and middle-income countries. Unlike infectious disease, malignancy and other chronic conditions require significant supportive infrastructure for diagnostics, ...
Early death and treatment-related mortality: A report from SUCCOUR - Supportive Care for Children with Cancer in Africa

Njuguna, Festus; Chagaluka, George; Kouya, Francine (PubMed, 2021)

Background: Deaths during paediatric cancer treatment are common in Africa. It is often difficult to distinguish between treatment-related and disease-related causes. To prevent these deaths, it is important to study them ...
Esophageal cancer, the topmost cancer at MTRH in the rift valley, Kenya, and its potential risk factors

Kirtika Patel, Johnston Wakhisi, Simeon Mining, Ann Mwangi, Radheka Patel (Hindawi Publishing Corporation, 2013-10)

Esophageal cancer at Moi Teaching and Referral Hospital (MTRH) is the leading cancer in men with a poor prognosis. A case control study (n = 159) aimed at the histology type, gender, and risk indicators was carried out at ...
Factors Associated with Uptake of Visual Inspection with Acetic Acid (VIA) for Cervical Cancer Screening in Western Kenya

Orang’o, Elkanah Omenge; Wachira, Juddy; Asirwa, Fredrick Chite; Busakhala, Naftali; Naanyu, Violet; Kisuya, Job; Otieno, Grieven; Keter, Alfred; Mwangi, Ann (Crossmark, 2016)

Purpose Cervical cancer screening has been successful in reducing the rates of cervical cancer in developed countries, but this disease remains the leading cause of cancer deaths among women in sub-Saharan Africa. We ...
Improvement of pathology in sub-Saharan Africa

Chumba, David Kiprop; Wabinga, Henry (The Lancet, 2013-04)

In the coming decades, cancer will be a major clinical and public health issue in sub-Saharan Africa. However, clinical and public health infrastructure and services in many countries are not positioned to deal with the ...
Medicinal plants used for treating cancer in Kenya: an ethnopharmacological overview

Omara, Timothy; Odero, Mark Peter; Obakiro, Samuel Baker (Springer, 2022)

Background: Cancer is one of the major causes of mortality worldwide. Though 30% of cancers can be treated when detected at early stages, their treatment has been compounded by resistance of tumor cells to anticancer ...
Medicinal plants used in traditional management of cancer in Uganda: A review of ethnobotanical surveys, phytochemistry, and anticancer studies

Mbabaz, Immaculate; Omara, Timothy; Kiprop, Ambrose K.; Ramkat, Rose C.; Cherutoi, Jackson; Kagoya, Sarah; Nyangena, Decrah Moraa; Karanja, Lucy Nyambura; Jephchirchir, Abigael; Maiyo, Alfaiyo; Kiptui, Betty Jematia; Nakiguli, Caroline Kiwanuka; Nakabuye, Brenda Victoria; Koske, Margaret Chepkemoi (Hindawi Publishing Corporation, 2020)

The burden of neoplastic diseases is a significant global health challenge accounting for thousands of deaths. In Uganda, about 32,617 cancer cases were reported in 2018, accompanied by 21,829 deaths. In a view to identify ...
Pharmacogenomics of vincristine-induced peripheral neuropathy in children with cancer: a systematic review and meta-analysis

Uittenboogaard, Aniek; Neutel, Céline L.G.; Ket, Johannes C. F.; Njuguna, Festus; Huitema, Alwin D. R.; Kaspers, Gertjan J. L.; Velde, Mirjam E. van de (PMC, 2022-01-26)

: Vincristine-induced peripheral neuropathy (VIPN) is a debilitating side-effect of vincristine. It remains a challenge to predict which patients will suffer from VIPN. Pharmacogenomics may explain an individuals’ ...
Pitfalls of practicing cancer epidemiology in resource-limited settings: the case of survival and loss to follow-up after a diagnosis of Kaposi’s sarcoma in five countries across sub-Saharan Africa

Freeman, Esther; Semeere, Aggrey; Wenger, Megan; Bwana, Mwebesa; Asirwa, F. Chite; Busakhala, Naftali; Oga, Emmanuel; Jedy-Agba, Elima; Kwaghe, Vivian; Iregbu, Kenneth; Jaquet, Antoine; Dabis, Francois; Yumo, Habakkuk Azinyui; Dusingize, Jean Claude; Bangsberg, David; Anastos, Kathryn; Phiri, Sam; Bohlius, Julia; Egger, Matthias; Yiannoutsos, Constantin; Wools-Kaloustian, Kara (Biomed central, 2016-02-06)

Background: Survival after diagnosis is a fundamental concern in cancer epidemiology. In resource-rich settings, ambient clinical databases, municipal data and cancer registries make survival estimation in real-world ...
Pitfalls of practicing cancer epidemiology in resource-limited settings: the case of survival and loss to follow-up after a diagnosis of Kaposi’s sarcoma in five countries across sub-Saharan Africa

Freeman, Esther; Semeere, Aggrey; Wenger, Megan; Bwana, Mwebesa; Asirwa, F. Chite; Busakhala, Naftali; Oga, Emmanuel; Jedy-Agba, Elima; Kwaghe, Vivian; Iregbu, Kenneth; Jaquet, Antoine; Dabis, Francois; Yumo, Habakkuk Azinyui; Dusingize, Jean Claude; Bangsberg, David; Anastos, Kathryn; Phiri, Sam; Bohlius, Julia; Egger, Matthias; Yiannoutsos, Constantin; Wools-Kaloustian, Kara; Martin, Jeffrey (BMC, 2016-02)

Background: Survival after diagnosis is a fundamental concern in cancer epidemiology. In resource-rich settings, ambient clinical databases, municipal data and cancer registries make survival estimation in real-world ...
Pitfalls of practicing cancer epidemiology in resource-limited settings: the case of survival and loss to follow-up after a diagnosis of Kaposi’s sarcoma in five countries across sub-Saharan Africa

Freeman, Esther; Semeere, Aggrey; Wenger, Megan; Bwana, Mwebesa; Asirwa, F. Chite; Busakhala, Naftali; Oga, Emmanuel; Jedy-Agba, Elima; Vivian Kwaghe Kwaghe, Vivian Kwaghe; Iregbu, Kenneth; Jaquet, Antoine; Dabis, Francois; Azinyui Yumo, Habakkuk; Dusingize, Jean Claude; Bangsberg, David; Anastos, Kathryn; Phiri, Sam; Bohlius, Julia; Egger, Matthias; Yiannoutsos, Constantin; Wools-Kaloustian, Kara; Martin, Jeffrey (bmc, 2016-02-06)

Background: Survival after diagnosis is a fundamental concern in cancer epidemiology. In resource-rich settings, ambient clinical databases, municipal data and cancer registries make survival estimation in real-world ...

Now showing items 1-20 of 31

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