dc.contributor.author |
Snelgrove, John W. |
|
dc.contributor.author |
Alera, Joy Marsha |
|
dc.contributor.author |
Foster, Michael C. |
|
dc.contributor.author |
Bett, Kipchumba C. N. |
|
dc.contributor.author |
Bloomfield, Gerald S. |
|
dc.contributor.author |
Silversides, Candice K. |
|
dc.contributor.author |
Barasa, Felix A. |
|
dc.contributor.author |
Christoffersen-Deb, Astrid |
|
dc.contributor.author |
Millar, Heather C. |
|
dc.contributor.author |
Thorne, Julie G. |
|
dc.contributor.author |
Spitzer, Rachel F. |
|
dc.contributor.author |
Vedanthan, Rajesh |
|
dc.contributor.author |
Okun, Nanette |
|
dc.date.accessioned |
2022-09-29T07:30:38Z |
|
dc.date.available |
2022-09-29T07:30:38Z |
|
dc.date.issued |
2021-02-09 |
|
dc.identifier.uri |
https://doi.org/10.5334/gh.826 |
|
dc.identifier.uri |
http://ir.mu.ac.ke:8080/jspui/handle/123456789/6832 |
|
dc.description.abstract |
Background: Rheumatic heart disease (RHD) in sub-Saharan Africa contributes to significant
cardiac morbidity and mortality, yet prevalence estimates of RHD lesions in pregnancy are
lacking.
Objectives: Our first aim was to evaluate women using echocardiography to estimate the prev-
alence of RHD and other cardiac lesions in low-risk pregnancies. Our second aim was to assess
the feasibility of screening echocardiography and its acceptability to patients.
Methods: We prospectively recruited 601 pregnant women from a low-risk antenatal clinic
at a tertiary care maternity centre in Western Kenya. Women completed a questionnaire
about past medical history and cardiac symptoms. They underwent standardized screening
echocardiography to evaluate RHD and non-RHD associated cardiac lesions. Our primary out-
come was RHD-associated cardiac lesions and our secondary outcome was a composite of any
clinically-relevant cardiac lesion or echocardiography finding. We also recorded duration of
screening echocardiography and its acceptability among pregnant women in this sample.
Results: The point prevalence of RHD-associated cardiac lesions was 5.0/1,000 (95% confidence
interval: 1.0–14.5), and the point prevalence of all clinically significant lesions/findings was
21.6/1,000 (11.6–36.7). Mean screening time was seven minutes (SD 1.7, range: 4–17) for women
without cardiac abnormalities and 13 minutes (SD 4.6, range: 6–23) for women with abnormal
findings. Echocardiography was acceptable to women with 74.2% agreeing to participate.
Conclusions: The prevalence of clinically-relevant cardiac lesions was moderately high in a low-
risk population of pregnant women in Western Kenya. |
en_US |
dc.language.iso |
en |
en_US |
dc.publisher |
PMC |
en_US |
dc.subject |
Rheumatic heart disease |
en_US |
dc.subject |
Pregnancy |
en_US |
dc.subject |
Echocardiography |
en_US |
dc.subject |
Epidemiology |
en_US |
dc.title |
Prevalence of rheumatic heart disease and other cardiac conditions in low-risk pregnancies in Kenya: A prospective echocardiography screening study |
en_US |
dc.type |
Article |
en_US |