School of Medicine: Recent submissions

Now showing items 1721-1740 of 2401

Can the financial burden of being a community health volunteer in western Kenya exacerbate poverty?

Kelly, Alyssa; Mitra, Sanjana; Elung’at, Justus; Songok, Julia; Jackson, Suzanne; Christoffersen-Deb, Astrid (Health Promotion International, 2020)

Community health volunteers (CHVs) act as vital links between communities and health facilities, bridging the health service delivery gap common in low- and middle-income countries. In 2013, changes in funding in western ...
Loop electrosurgical excision procedure treats cervical intraepithelial neoplasia 2/3 among HIV- and HIV+ women in Kenya

Mehta, Naaman; Orang'o, Omenge; Itsura, Peter; Tonui, Philip; Bussmann, Hermann; Bogers, JP; Liu, Tao; Cu-Uvin, Susan (Wolters Kluwer, 2020)

Objective The aim of the study was to compare loop electrosurgical excision procedure (LEEP) as treatment for cervical intraepithelial neoplasia (CIN) 2/3 in HIV− versus HIV+ women. Materials and Methods Seventy-five HIV− ...
Trans-anal protrusion of intussusception.

Mburu, Elias; Akello, Walter; Kimani, Winfred; Saula, P.W.; Kuremu, R.T. (Elsevier, 2020)

Intussusception is a common cause of intestinal obstruction in infants and toddlers. Uncommon presentation with a mass protruding from the anus is often misdiagnosed as rectal prolapse when a high index of suspicion is not ...
Evaluating the impact of a 15-year academic partnership to promote sustainable engagement, education, and scholarship in global health

Karwa, Rakhi; Schellhase, Ellen; Manji, Imran; Fletcher, Sara; Jakait, Beatrice; Kipyegon, Victor; Crowe, Susie; Miller, Monica L. (Journal of the American College of Clinical Pharmacy, 2020)

Introduction: In 2003, Purdue University College of Pharmacy (PUCOP) in West Lafa- yette, Indiana, began the Purdue Kenya Partnership (PKP) in collaboration with the Academic Model Providing Access to Healthcare, Moi ...
The double burden of overnutrition and undernutrition in mother−child dyads in Kenya: demographic and health survey data, 2014

Masibo, Peninah Kinya; Humwa, Felix; Macharia, Teresia Njoki (Cambridge University press, 2019)

The double burden of over nutrition and under nutrition is rapidly becoming a public health concern in low- and middle-income countries. We explored the occurrence of mother−child pairs of over- and under nutrition and the ...
Low-coverage sequencing cost-effectively detects knownand novel variation in underrepresented populations

Martin, Alicia R.; Atkinson, Elizabeth G.; Ashaba, Fred K.; Atwoli, Lukoye; Gichuru, Stella; Injera, Wilfred E.; Kariuki, Symon M.; Roxanne, James; Kigen, Gabriel; Dodge, Sheila; Stevenson, Anne (bioRxiv, 2020)

Background Genetic studies of biomedical phenotypes in underrepresented populations identify disproportionate numbers of novel associations. However, current genomics infrastructure--including most genotyping arrays and ...
Practical and ethical solutions for remote applied learning experiences in global health

Kalbarczyk, Anna; Harrison, Meagan; Sanguineti, Maria Cecilia Dedios; Wachira, Juddy; Guzman, Carlos A. Faerron; Hansoti, Bhakti (Annals of global health, 2020)

Global health trainees rely on immersive experiences to apply their classroom knowledge in real-world settings. However, during the COVID-19 pandemic travel has come to a halt and short-term experiences are no longer ...
Low sensitivity of the careHPVTM Assay for detection of Oncogenic Human Papillomavirus in cervical samples from HIV-infected and HIV-uninfected Kenyan women

Chelimo K (International Journal of Clinical Virology, 2020)

ackground: Human papillomavirus (HPV) infection causes cervical cancer (CC), a common malignancy among Kenyan women. New CC screening methods rely on oncogenic HPV (“high- risk”, or HR-HPV) detection, but most have not ...
The reproductive health fall-out of a global pandemic

Brianne, Lewis; Spitzer, Rachel F.; Caitlin, Bernard; Wawuda, Righa; Buitendyk, Marie (Informa UK Limited, 2020)

Social media outlets are inundated with quips about the baby boom coming nine months after the COVID-19 pandemic. It’s not that funny. Or that simple. The global spread of the coronavirus has resulted in unprecedented ...
Promoting positive maternal, newborn, andchild health behaviors through a group-based health education and microfinanceprogram: a prospective matched cohortstudy in western Kenya

Maldonado, Lauren Y.; Songok, Julia J.; Snelgrove, John W.; Ochieng, Christian B.; Chelagat, Sheilah; Ikemeri, Justus E.; Okwanyi, Monica A.; Cole, Donald C.; Ruhl, Laura J.; Astrid, Christoffersen-Deb (Springer, 2020)

Background:Chamas for Change(Chamas)is a group-based health education and microfinance program for pregnant and postpartum women that aims to address inequities contributing to high rates of maternal and infant mortality ...
Nevirapine Versus Lopinavir/Ritonavir-Based Initial Therapy for HIV-1 Infection among Women in Africa: A Randomized Trial

Lockman, Shahin; Hughes, Michael; Sawe, Fred; Kimaiyo, Sylvester; Chipato, Tsungai; Aida, Asmelash (Amapth, 2012-06)

Nevirapine (NVP) is widely used in antiretroviral treatment (ART) of HIV-1 globally. The primary objective of the AA5208/OCTANE trial was to compare the efficacy of NVP-based versus lopinavir/ritonavir (LPV/r)-based initial ...
Challenges of HIV Lymphoma clinical trials in Africa: Lessons from the AIDS malignancy Consortium 068 Study

Busakhala, Naftali; Omoding, Abrahams (American Society of Clinical Oncology, 2020)

The purpose of this article is to describe lessons from the first lymphoma clinical trial conducted by the AIDS Malignancy Consortium (AMC) in sub-Saharan Africa (SSA). AMC-068 was a randomized phase II comparison of ...
Expanding point-of-care ultrasound training in a low- and middle-income country: experiences from a collaborative short-training workshop in Kenya

Jones, Leanne; Gathu, Catherine; Szkwarko, Daria; Mucheru, Sam; Amin, Naushad; Amisi, James A; Bergman, Kevin; Ramos, Mena; Jayasekera, Neil (Fam Med, 2020)

Background and objectives: In Kenya, little data exists on point-of-care ultrasound (POCUS) training and use for family medicine physicians. In 2017, a 3-day POCUS workshop assembled most of the family medicine physicians ...
High burden of cardiac disease in pregnancy at a National Referral Hospital in Western Kenya

Lumsden, Rebecca; Barasa, Felix; Park, Lawrence P.; Ochieng, Christian B.; Alera, Joy M.; Millar, Heather C.; Bloomfield, Gerald S.; Christoffersen, Astrid (PMC, 2020)

Background: Cardiac disease is a leading cause of non-obstetric maternal death worldwide, but little is known about its burden in sub-Saharan Africa.Objectives and Methods: We conducted a retrospective case-control study ...
Pre-marital predictors of marital violence in the WHO World Mental Health (WMH) Surveys

Atwoli, Lukoye (Springer, 2020)

Purpose Intimate partner violence (IPV) is a pervasive public health problem. Existing research has focused on reports from victims and few studies have considered pre-marital factors. The main objective of this study ...
Mental health response to the COVID-19 pandemic in Kenya: a review

Jaguga, Florence; Kwobah, Edith (Mental health response to the COVID-19 pandemic in Kenya: a review, 2020)

Abstract Background: The COVID-19 pandemic has exerted considerable impact on public mental health globally. With the pandemic rapidly rising in sub-Saharan Africa including Kenya, there is need to provide evidence to guide ...
HIV and cardiovascular disease

Bloomfield, Gerald S; Njuguna, Benson (Lancet, 2020-04)

HIV-related cardiovascular disease research is predominantly from Europe and North America. Of the estimated 37·9 million people living with HIV worldwide, 25·6 million live in sub-Saharan Africa. Although mechanisms for ...
“To speak of death is to invite it”: provider perceptions of palliative care for cardiovascular patients in Western Kenya

Love, Keith R.; Karin, Elizabeth; Morogo, Daniel; Toroitich, Florence; Boit, Juli M.; Tarus, Allison; Barasa, Felix A.; Goldstein, Nathan E.; Koech, Myra; Vedanthan, Rajesh (Elsevier, 2020)

Context Cardiovascular disease (CVD) is the leading cause of death globally and a significant health burden in Kenya. Despite improved outcomes in CVD, palliative care has limited implementation for CVD in low-income and ...
PS-SiZer map to investigate significant features of body-weight profile changes in HIV infected patients in the IeDEA Collaboration

Harezlak, Jaroslaw; Sarwat, Samiha; Wools-Kaloustian, Kara; Schomaker, Michael; Balestre, Eric; Law, Matthew (PLOS ONE, 2020)

ObjectivesWeextendthemethodof SignificantZeroCrossingsof Derivatives(SiZer)to address within-subject correlations of repeatedly-collected longitudinal biomarker data and the computational aspects of themethodology when ...
The role of dermatology in Kaposi sarcoma diagnosis across three regions in sub-Saharan Africa

Mukendi, Kayembe (Elsevier, 2020)

This work was supported by a Dermatology Foundation Career Development Award (Freeman). Research reported in this publication was also supported by the National Institute of Allergy and Infectious Diseases (NIAID) and the ...

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