| dc.contributor.author | Campbell, Mary S. | |
| dc.contributor.author | Kahle, Erin M. | |
| dc.contributor.author | Celum, Connie | |
| dc.contributor.author | Lingappa, Jairam R. | |
| dc.contributor.author | Kapiga, Saidi | |
| dc.date.accessioned | 2021-07-27T09:01:08Z | |
| dc.date.available | 2021-07-27T09:01:08Z | |
| dc.date.issued | 2013 | |
| dc.identifier.uri | https://doi.org/10.1093/infdis/jit015 | |
| dc.identifier.uri | http://ir.mu.ac.ke:8080/jspui/handle/123456789/4942 | |
| dc.description.abstract | Recent data suggest that infection with human immunodeficiency virus type 1 (HIV-1) subtype C results in prolonged high-level viremia (>5 log10 copies/mL) during early infection. We examined the relationship between HIV-1 subtype and plasma viremia among 153 African seroconverters. Mean setpoint viral loads were similar for C and non-C subtypes: 4.36 vs 4.42 log10 copies/mL (P = .61). The proportion of subtype C–infected participants with viral loads >5 log10 copies/mL was not greater than the proportion for those with non-C infection. Our data do not support the hypothesis that higher early viral load accounts for the rapid spread of HIV-1 subtype C in southern Africa. | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | Oxford University Press | en_US |
| dc.subject | Plasma viral load | en_US |
| dc.subject | HIV-1 infection | en_US |
| dc.title | Plasma viral loads during early HIV-1 infection are similar in subtype C–and non-subtype C–infected African seroconverters | en_US |
| dc.type | Article | en_US |
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