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Evaluation of five immunodiagnostic techniques in echinococcosis patients

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dc.contributor.author Chemtai, Alex K.
dc.contributor.author Bowry, T. R.
dc.contributor.author Ahmad, Z.
dc.date.accessioned 2021-06-17T08:07:52Z
dc.date.available 2021-06-17T08:07:52Z
dc.date.issued 1981
dc.identifier.uri http://ir.mu.ac.ke:8080/jspui/handle/123456789/4654
dc.description.abstract Double diffusion (DD), indirect haemagglutination (IHA), immunoelectrophoresis (IEP), latex agglutination (LA), and complement fixation (CF) tests were evaluated for sensitivity and specificity in the diagnosis of 141 surgically-proven Turkana echinococcosis patients and 10 controls. The overall sensitivities for the tests were: IHA, 86.7%; LA, 53.3%; CF, 63.3%; DD, 55.0%; IEP, 55.0%. LA and CF tests produced a high number of false positive results; IHA gave a false positive result in 10% of cases; no false positives were obtained with IEP and DD. A combination of the latter three tests would therefore offer the best chance of detecting specific anti-Echinococcus antibodies, with an average sensitivity of 62.7%. The possible reasons for the relatively high incidence of false negative values are discussed. en_US
dc.language.iso en en_US
dc.publisher World Health Organisation en_US
dc.subject Echinococcosis patients en_US
dc.subject Immunodiagnostic technique en_US
dc.title Evaluation of five immunodiagnostic techniques in echinococcosis patients en_US
dc.type Article en_US


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