dc.contributor.author | Gitonga, Lawrence Kirimi | |
dc.contributor.author | Boru, Waqo Gufu | |
dc.contributor.author | Kwena, Arthur M. | |
dc.contributor.author | Maritim, Marybeth | |
dc.contributor.author | Wamicwe, Joyce | |
dc.contributor.author | Ransom, James | |
dc.date.accessioned | 2021-05-19T07:00:36Z | |
dc.date.available | 2021-05-19T07:00:36Z | |
dc.date.issued | 2019 | |
dc.identifier.uri | https://doi.org/10.1186/s13104-019-4829-4 | |
dc.identifier.uri | http://ir.mu.ac.ke:8080/jspui/handle/123456789/4452 | |
dc.description.abstract | Objectives:The objective of this study was to evaluate the performance of lateral flow immunoassay (LFA) against latex agglutination (LA), India ink and culture in point-of-care diagnosis of cryptococcus meningitis (CM). We con-ducted cross-sectional study among HIV-positive patients with suspected CM at Mbagathi Hospital, Nairobi, April–July 2017.Results:Of 124 capillary blood and serum and 99 cerebrospinal fluid (CSF) samples, LFA and LA had a concurrence on serum of 94.4%, kappa (0.88), sensitivity (100%) and specificity (91%). LFA and LA on CSF, was 97.9%, kappa (0.96), sensitivity (100%) and specificity (96%). LFA and India ink was 96.9%, kappa (0.94), sensitivity (100%) and specificity (94.1%). On CSF culture, concurrence was 72.7%, kappa (0.43), sensitivity (100%) and specificity (64%) and of LFA on capillary blood, serum and CSF was 100% with kappa (1.00), sensitivity and specificity of 100% | en_US |
dc.language.iso | en | en_US |
dc.publisher | BioMed Central | en_US |
dc.subject | Point of care testing evaluation | en_US |
dc.subject | Cryptococcus meningitis | en_US |
dc.title | Point of care testing evaluation of lateral flow immunoassay for diagnosis of cryptococcus meningitis in HIV-positive patients at an urban hospital in Nairobi, Kenya, 2017 | en_US |
dc.type | Article | en_US |
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