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Cardiovascular complications of HIV in endemic countries

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dc.contributor.author Bloomfield, Gerald S.
dc.contributor.author Bogorodskaya, Milana
dc.date.accessioned 2020-07-29T19:10:17Z
dc.date.available 2020-07-29T19:10:17Z
dc.date.issued 2016
dc.identifier.uri http://ir.mu.ac.ke:8080/jspui/handle/123456789/3196
dc.description.abstract Effective combination antiretroviral therapy (ART) has enabled human immunodeficiency virus (HIV) infection to evolve from a generally fatal condition to a manageable chronic disease. This transition began two decades ago in high-income countries, and has more recently begun in lower income, HIV endemic countries (HIV-ECs). With this transition, has come a concurrent shift in clinical and public health burden from AIDS-related complications and opportunistic infections, to those associated with well-controlled HIV disease, including cardiovascular disease (CVD). In the current treatment era, traditional CVD risk factors and HIV-related factors both contribute to an elevated risk of myocardial infarction, stroke, heart failure, and arrhythmias. In HIV-ECs, the high prevalence of persons living with HIV and growing prevalence of CVD risk factors will contribute to a growing epidemic of HIV-associated CVD. In this review, we discuss the epidemiology and pathophysiology of cardiovascular complications of HIV and the resultant implications for public health efforts in HIV-ECs. en_US
dc.language.iso en en_US
dc.publisher PMC en_US
dc.subject Cardiovascular en_US
dc.subject HIV en_US
dc.subject Endemic en_US
dc.title Cardiovascular complications of HIV in endemic countries en_US
dc.type Article en_US


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