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Pairwise and three-country comparisons of high and low COVID-19 vaccination rates in 12 African countries: a mixed- method study protocol

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dc.contributor.author Ezezika, Obidimma
dc.contributor.author Luginaa, Isaac N
dc.contributor.author Sonko, Bakary
dc.contributor.author Olorunbiyi, Omolola
dc.contributor.author Amponsah-Dacosta, Edina
dc.contributor.author Ameyaw, Edward Kwabena
dc.contributor.author Omwenga, Eric Omori
dc.contributor.author Kandala, Ngianga- Bakwin
dc.contributor.author Djuidje-Ngounoue, Marceline
dc.contributor.author Raimi, Morufu
dc.contributor.author Surakat, Olabanji
dc.contributor.author Ariyo, Oluwaseun
dc.contributor.author Malande, Ombeva Oliver
dc.contributor.author Mong’are, Samuel
dc.contributor.author Demi, Suleyman M
dc.contributor.author Ndodo, Nnaemeka
dc.contributor.author Quibrantar, Selina
dc.contributor.author Kishif, Fatima
dc.contributor.author Abdullahi, Musa
dc.contributor.author Edor, Joseph
dc.contributor.author Elemuwa, Chris
dc.contributor.author Obiageli, Nebe
dc.contributor.author Ogunwale, Akintayo O
dc.contributor.author Nakatugga, Rachel Afaayo
dc.contributor.author Zelalem, Mesert
dc.date.accessioned 2026-07-06T08:22:14Z
dc.date.available 2026-07-06T08:22:14Z
dc.date.issued 2026-05
dc.identifier.uri file:///home/systems/Downloads/e114816.full.pdf
dc.identifier.uri http://ir.mu.ac.ke:8080/jspui/handle/123456789/10296
dc.description.abstract The COVID- 19 pandemic has highlighted significant disparities in vaccine uptake across sub- Saharan Africa, yet research exploring the regional and country-specific factors influencing these rates remains limited. Understanding these factors is crucial for developing targeted regional and global public health interventions to improve vaccination uptake and strengthen pandemic preparedness. This study aims to fill a critical knowledge gap by assessing the factors influencing vaccination rates across sub-Saharan Africa at the operational, systemic and socio-political levels. Methods and analysis The study will employ a comparative case study design across 12 African countries to examine context-specific factors influencing pandemic vaccine preparedness. The 12 selected countries (Angola, Botswana, Burundi, Cameroon, Côte d'Ivoire, Malawi, Namibia, Nigeria, Rwanda, Senegal, South Africa and Uganda) will be categorised by vaccination rate (high, moderate or low). The study will integrate quantitative and qualitative data to provide comprehensive insights. Quantitative data, including COVID-19, macroeconomic, health system and governance indicators, will be sourced from reputable online portals, such as the WHO, the World Bank and Our World in Data. Qualitative data will be collected through key informant interviews with experts across participating African countries, except Angola. Due to delays in obtaining ethics approval in Angola, no primary data collection including key informant interviews will be conducted in Angola unless ethics approval is obtained. Angola will therefore be included through a secondary data approach, drawing on publicly available reports, published literature and relevant case studies. All qualitative data will be analysed using thematic analysis, and quantitative data will be analysed using descriptive methods. Ethics and dissemination Ethics approval was obtained from Western University’s Health Sciences Research Ethics Board (126398) and relevant bodies in the 11 participating countries. Findings will be shared through reports to public health authorities, policy briefs and presentations at academic conferences and peer-reviewed publications en_US
dc.language.iso en en_US
dc.publisher BMJ Group en_US
dc.subject COVID 19 en_US
dc.subject Pandemic en_US
dc.subject Vaccination en_US
dc.title Pairwise and three-country comparisons of high and low COVID-19 vaccination rates in 12 African countries: a mixed- method study protocol en_US
dc.type Article en_US


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