1. Moi University Open Access Repository

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Results 1-10 of 17 (Search time: 0.002 seconds).
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Issue DateTitleAuthor(s)
2013-07Nutritional Status of Orphaned and Separated Children and Adolescents Living in Community and Institutional Environments in Uasin Gishu County, KenyaNyandiko Winstone M.; Kamanda Allan.; Braitstein Paula.; Koech Julius.; Ayaya Samuel.; Gisore Peter.; Atwoli Lukoye.; Vreeman Rachel C.; Duefield Corey.; Ayuku David O.
2013-07HIV Testing Uptake and Prevalence Among Adolescents and Adults in a Large Home-Based HIV Testing Program in Western KenyaWachira Juddy.; Ndege Samson.; Koech Julius.; Braitstein Paula.; Ayuo Paul.
2012-07-31Psychiatric morbidity among HIV-infected children and adolescents in a resource-poor Kenyan urban communityLukoye Atwoli; Kangethe Rachael; Muthoni Mathai; Wangari Kuria; Kamau Judy W.
2014A qualitative assessment of barriers to antiretroviral therapy adherence among adolescents in Western Kenya.Kunapareddy, Catherine June; Nyandiko, Winstone; Inui, Thomas; Ayaya, Samuel; Marrero, David G.; Vreeman, Rachel
2014Prevalence of sexually transmitted infections including HIV in street-connected adolescents in western KenyaChirchir, Amon K; Ayuku, David; Koech, Julius; Nyandiko, Winstone
2016HIV Stigma: Perspectives from Kenyan Child Caregivers and Adolescents Living with HIVNyandiko, Winstone M.; Aluoch, Josephine; Naanyu, Violet
2017Experiences along the HIV care continuum: Perspectives of Kenyan adolescents and caregiversLuseno, Winnie K.; Mbai, Isabella; Otieno, Florence
2019Accelerometry-based physical activity assessment for children and adolescentsKostabel, Kenn; Ojiambo, Robert
2019Accelerometry-based physical activity assessment for children and adolescentsKostabel, Kenn; Ojiambo, Robert
2012Self-report of sexual behavior among adolescents is notoriously inconsistent, yet such measures are commonly used as outcomes for human immunodeficiency virus (HIV) prevention interven- tion trials. There has been a growing interest in the use of HIV and other sexually transmitted disease bio- markers as more valid measures of intervention impact in high HIV prevalence areas, particularly in sub- Saharan Africa. We examine the challenges, benefits, and feasibility of including HIV and herpes simplex virus type 2 (HSV-2) biomarker data, with details about different data collection and disclosure methods from two adolescent prevention trials in Kenya and Zimbabwe. In Kenya, whole blood samples were collected using venipuncture; adult guardians were present during biomarker procedures and test results were disclosed to participants and their guardians. In contrast, in Zimbabwe, samples were collected using finger pricks for dried blood spots (DBS); guardians were not present during biomarker procedures, and results were not disclosed to participants and/or their guardians. In both countries, prevalence in the study samples was low. Although the standard of care for testing for HIV and other sexually transmitted infec- tions includes disclosure in the presence of a guardian for adolescents under age 18, we conclude that more research about the risks and benefits of disclosure to adolescents in the context of a clinical trial is needed. Notably, current serological diagnosis for HSV-2 has a low positive predictive value when prevalence is low, resulting in an unacceptable proportion of false positives and serious concerns about disclosing test results to adolescents within a trial. We also conclude that the DBS approach is more convenient and efficient than venipuncture for field research, although both approaches are feasible.Mbai, Isabella I; Itindi, Janet

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