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DC Field | Value | Language |
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dc.contributor.author | Navuluri, Neelima | - |
dc.contributor.author | Lagat, David | - |
dc.contributor.author | Egger, Joseph R. | - |
dc.contributor.author | Birgen, Elcy | - |
dc.contributor.author | Diero, Lameck | - |
dc.contributor.author | Murdoch, David M. | - |
dc.contributor.author | Thielman, Nathan | - |
dc.contributor.author | Kussin, Peter S. | - |
dc.contributor.author | Que, Loretta G. | - |
dc.contributor.author | Paul, Devon | - |
dc.date.accessioned | 2024-05-09T07:33:43Z | - |
dc.date.available | 2024-05-09T07:33:43Z | - |
dc.date.issued | 2023-08-17 | - |
dc.identifier.uri | https://doi.org/10.3389/ijph.2023.1606030 | - |
dc.identifier.uri | http://ir.mu.ac.ke:8080/jspui/handle/123456789/9070 | - |
dc.description.abstract | Objectives: Determine the prevalence of airway disease (e.g., asthma, airflow obstruction, and eosinophilic airway inflammation) in Kenya, as well as related correlates of airway disease and health-related quality of life. Methods: A three-stage, cluster-randomized cross-sectional study in Uasin Gishu County, Kenya was conducted. Individuals 12 years and older completed questionnaires (including St. George’s Respiratory Questionnaire for COPD, SGRQ-C), spirometry, and fractional exhaled nitric oxide (FeNO) testing. Prevalence ratios with 95% confidence intervals (CIs) were calculated. Multivariable models were used to assess correlates of airflow obstruction and high FeNO. Results: Three hundred ninety-two participants completed questionnaires, 369 completed FeNO testing, and 305 completed spirometry. Mean age was 37.5 years; 64% were women. The prevalence of asthma, airflow obstruction on spirometry, and eosinophilic airway inflammation was 21.7%, 12.3% and 15.7% respectively in the population. Women had significantly higher SGRQ-C scores compared to men (15.0 vs. 7.7). Wheezing or whistling in the last year and SGRQ-C scores were strongly associated with FeNO levels >50 ppb after adjusting for age, gender, BMI, and tobacco use. Conclusion: Airway disease is a significant health problem in Kenya affecting a young population who lack a significant tobacco use history. | en_US |
dc.description.sponsorship | (NHLBI) | en_US |
dc.language.iso | en | en_US |
dc.publisher | IJPH | en_US |
dc.subject | Asthma | en_US |
dc.subject | Airflow obstruction | en_US |
dc.subject | Eosinophilic airway inflammation | en_US |
dc.title | Asthma, Airflow Obstruction, and Eosinophilic Airway Inflammation Prevalence in Western Kenya: A Population-Based Cross-Sectional Study | en_US |
dc.type | Article | en_US |
Appears in Collections: | School of Medicine |
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