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Title: | Screening for tuberculosis in pregnancy: do we need more than a symptom screen? Experience from western Kenya |
Authors: | Kosgei, R. J. Szkwarko, D. Callens, S. Gichangi, P. Temmerman, M. Kihara, A-B. Sitienei, J. J. Cheserem, E. J. Ndavi, P. M. A. J. Reid, A. J. Carter, E. J. |
Keywords: | TB symptom screening Questionnaire TB Diagnosis |
Issue Date: | 21-Nov-2013 |
Publisher: | The Union |
Abstract: | Objectives: 1) To explore the utility of tuberculosis (TB) symptom screening for symptoms of ⩾2 weeks’ duration in a routine setting, and 2) to compare differences in TB diagnosis between human immunodeficiency virus (HIV) infected and non-HIV-infected pregnant women in west- ern Kenya. Design: Comparative cross-sectional study among preg- nant women with known HIV status screened for TB from 2010 to 2012, in Eldoret, western Kenya. Results: Of 2983 participants, respectively 34 (1%), 1488 (50.5%) and 1461 (49.5%) had unknown, positive and negative HIV status. The median age was respectively 30 years (interquartile range [IQR] 26–35) and 26 years (IQR 24–31) in HIV-infected and non-infected participants. A positive symptom screen was found in respectively 8% (119/1488) and 5% (67/1461) of the HIV-infected and non-infected women. The median CD4 count at en- rolment was 377 cells/μl (IQR 244–530) for HIV-infected women. One non-HIV-infected patient was sputum- p ositive. For HIV-infected women, TB was presumptively treated in 1% (16/1488) based on clinical symptoms and chest X-ray. Cumulatively, anti-tuberculosis treatment was offered to 0.6% (17/2949) of the participants. Conclusion: This study does not seem to demonstrate the utility of TB symptom screening questionnaires in a rou- tine setting among pregnant women, either HIV-infected or non-infected, in western Kenya. |
URI: | http://dx.doi.org/10.5588/pha.13.0073 http://ir.mu.ac.ke:8080/jspui/handle/123456789/9052 |
Appears in Collections: | School of Public Health |
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