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Title: | Cervical cancer management in a low resource setting: A 10-year review in a tertiary care hospital in Kenya |
Authors: | Shaffi, Afrin F. Odongo, Elly B. Itsura, Peter M. Tonui, Phillip K. Mburu, Anisa W. Hassan, Amina R. Rosen, Barry P. Covens, Allan L. |
Keywords: | Cervical cancer Radical hysterectomy Radiotherapy Low- and - middle-income countries |
Issue Date: | 9-Feb-2024 |
Publisher: | Elsevier |
Abstract: | Background: Cervical cancer is one of the leading causes of cancer mortality among women in Kenya due to late presentations, poor access to health care, and limited resources. Across many low- and middle-income countries infrastructure and human resources for cervical cancer management are currently insufficient to meet the high population needs therefore patients are not able to get appropriate treatment. Objective: This study aimed to describe the clinicopathological characteristics and the treatment profiles of cervical cancer cases seen at Moi Teaching and Referral Hospital (MTRH) Methods: This was a retrospective cross-sectional study conducted at MTRH involving the review of the electronic database and medical charts of 1541 patients with a histologically confirmed diagnosis of cervical cancer be- tween January 2012 and December 2021. Results: Of the 1541 cases analyzed, 91% were squamous cell carcinomas, 8% were adenocarcinomas, and 1% were other histological types. Thirty-eight percent of the patients were HIV infected and less than 30% of the women had health insurance. A majority (75%) of the patients presented with advanced-stage disease (stage IIB- IV). Only 13.9% received chemoradiotherapy with curative intent; of which 33.8% received suboptimal treat- ment. Of the 13% who received surgical treatment, 45.3% required adjuvant therapy, of which only 27.5% received treatment. Over 40% of the women were lost to follow-up. Conclusion: Most of the patients with cervical cancer in Kenya present at advanced stages with only a third receiving the necessary treatment while the majority receive only palliative treatment or supportive care. |
URI: | https://doi.org/10.1016/j.gore.2024.101331 http://ir.mu.ac.ke:8080/jspui/handle/123456789/9008 |
Appears in Collections: | School of Medicine |
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