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Title: | Comparison of total white blood cells and lymphocytes between pregnant and non-pregnant women infected with human immunodeficiency virus. |
Authors: | . Musyoki, Stanslaus K Mining, Simeon Nyongesa, Paul |
Keywords: | Achyranthus aspera Anti-pyretic activity Yeast Induce hyperpyrexia Ethanolic extract. |
Issue Date: | 11-Nov-2012 |
Publisher: | Asian Journal of Pharmaceutical and Health Sciences |
Abstract: | To determine and compare WBC and lymphocyte distribution between pregnant and non-pregnant women with HIV infection.Thirty-six pregnant HIV infected adult women not on antiretroviral therapy (ART) were compared with equal number of non-pregnant HIV infected women of similar characteristics. WBC and lymphocyte counts were obtained using a Coulter AcT5 five-part differential analyzer while lymphocytes cell subsets were done using a flow-cytometer. Statistical evaluations and comparisons between variables were by non-parametric computerized measures. Significance of the results was set at P<0.05. No statistically significant differences were found in the socio-economic and demographic characteristics of the study participants (P>0.299). Significant difference were observed in the total WBC (P=0.001), percentage lymphocyte counts, absolute and percent CD4 cell counts (P=0.004 and P=0.005 respectively) and CD4/CD8 ratio. Immune status of Pregnant HIV infected women is characterized of leucocytosis with lymhocytopenia and stable CD4 counts compared to non- pregnant HIV infected women. Larger Studies with more robust designs to confirm the present study findings. |
URI: | http://ir.mu.ac.ke:8080/jspui/handle/123456789/8931 |
Appears in Collections: | School of Medicine |
Files in This Item:
File | Description | Size | Format | |
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MINING.pdf | 569.08 kB | Adobe PDF | View/Open |
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