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http://ir.mu.ac.ke:8080/jspui/handle/123456789/8848
Title: | Population-based estimates and predictors of child and adolescent linkage to HIV care or death in Western Kenyaa |
Authors: | M. DeLong, Stephanie Xu, Yizhen L. Genberg, Becky Nyambura, Monicah Suzanne Goodrich, Suzanne Tarus, Carren Ndege, Samson W. Hogan, Joseph Braitstein, Paula |
Keywords: | HBCT, Adolescents, Population-based LInkage to HIV care, Children |
Issue Date: | 17-Jul-2023 |
Publisher: | Wolters Kluwer Health, Inc. |
Abstract: | Population-level estimates of linkage to HIV care among children and adolescents (CAs) can facilitate progress toward 95-95-95 goals. Setting: This study was conducted in Bunyala, Chulaimbo, and Teso North subcounties, Western Kenya. Methods: Linkage to care was defined among CAs diagnosed with HIV through Academic Model Providing Access to Healthcare (AMPATH)’s home-based counseling and testing initiative (HBCT) by merging HBCT and AMPATH Medical Record System data. Using follow-up data from Bunyala, we examined factors associated with linkage or death, using weighted multinomial logistic regression to account for selection bias from double-sampled visits. Based on the estimated model, we imputed the trajectory for each person in 3 subcounties until a simulated linkage or death occurred or until the end of 8 years when an individual was simulated to be censored. Results: Of 720 CAs in the analytic sample, 68% were between 0 and 9 years and 59% were female. Probability of linkage among CAs in the combined 3 subcounties was 48%–49% at 2 years and 64%–78% at 8 years while probability of death was 13% at 2 years and 19% at 8 years. Single or double orphanhood predicted linkage (adjusted odds ratio [aOR]: 2.66, 95% confidence interval [CI]: 1.33 to 5.32) and death (aOR: 9.85 [95% CI: 2.21 to 44.01]). Having a mother known to be HIV-positive also predicted linkage (aOR = 1.94, 95% CI: 0.97 to 3.86) and death (aOR: 14.49, 95% CI: 3.32 to 63.19). Conclusion: HIV testers/counselors should continue to ensure linkage among orphans and CAs with mothers known to be HIV- positive and also to support other CAs to link to HIV care. |
URI: | http://ir.mu.ac.ke:8080/jspui/handle/123456789/8848 |
Appears in Collections: | School of Medicine |
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