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http://ir.mu.ac.ke:8080/jspui/handle/123456789/7094
Title: | Esophageal Cancer, the Topmost Cancer at MTRH in the Rift Valley, Kenya, and Its Potential Risk Factors |
Authors: | Patel, Kirtika Wakhisi, Johnston Mining, Simeon Mwangi, Ann Patel, Radheka |
Keywords: | Esophageal Cancer Potential Risk Factors |
Issue Date: | Oct-2013 |
Abstract: | Esophageal cancer at Moi Teaching and Referral Hospital(MTRH) is the leading cancer in men with a poor prognosis. A case control study (� = 159) aimed at the histology type, gender, and risk indicators was carried out at MTRH. Mantel Haenszel chi-square and logistic regression were employed for analysis. Squamous-cell carcinoma was the common histological type occurring in the middle third portion of the oesophagus. Te occurrence of the cancer in males was 1.4 times that of females. Te mean age was 56.1 yrs. Low socioeconomic, smoking, snuff use, alcohol, tooth loss, cooking with charcoal and frewood, hot beverage, and use of mursik were independently associated with esophageal cancer (� < 0.05). Using logistic regression adjusted for various factors, alcohol consumption was associated with the increased risk of esophageal cancer. AHR was 0.45 and 95% CI: 0.205–0.985, � = 0.046. A societal component of low socioeconomic conditions, a lifestyle component with specifc practices such as the consumption of mursik, chang’a, busaa, snuff, smoking, hot tea, poor oral hygiene, and an environmental component with potential exposure to high levels of nitrosamines, passive smoking, and cooking with coal, could be involved. Te increase in experts at MTRH capable of diagnosing could be responsible for the increase in reporting this neoplasm. |
URI: | http://ir.mu.ac.ke:8080/jspui/handle/123456789/7094 |
Appears in Collections: | School of Medicine |
Files in This Item:
File | Description | Size | Format | |
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Patel Dr.pdf | 545.76 kB | Adobe PDF | View/Open |
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