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DC Field | Value | Language |
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dc.contributor.author | Mann, Marita | - |
dc.contributor.author | Diero, Lameck | - |
dc.contributor.author | Kemboi, Emmanuel | - |
dc.contributor.author | Mambo, Fidelis | - |
dc.contributor.author | Rono, Mary | - |
dc.contributor.author | Injera, Wilfred | - |
dc.contributor.author | Delong, Allison | - |
dc.contributor.author | Schreier, Leeann | - |
dc.contributor.author | Kaloustian, Kara W. | - |
dc.contributor.author | Sidle, John | - |
dc.contributor.author | Buziba, Nathan | - |
dc.contributor.author | Kantor, Rami | - |
dc.date.accessioned | 2022-10-06T09:28:57Z | - |
dc.date.available | 2022-10-06T09:28:57Z | - |
dc.date.issued | 2013-10 | - |
dc.identifier.uri | http://ir.mu.ac.ke:8080/jspui/handle/123456789/6900 | - |
dc.description.abstract | Background—Antiretroviral treatment interruptions (TIs) cause suboptimal clinical outcomes. Data on TIs during social disruption are limited. Methods—We determined effects of unplanned TIs after the 2007–2008 Kenyan postelection violence on virological failure, comparing viral load (VL) outcomes in HIV-infected adults with and without conflict-induced TI. Results—Two hundred and one patients were enrolled, median 2.2 years after conflict and 4.3 years on treatment. Eighty-eight patients experienced conflict-related TIs and 113 received continuous treatment. After adjusting for preconflict CD4, patients with TIs were more likely to have detectable VL, VL >5,000 and VL >10,000. Conclusions—Unplanned conflict-related TIs are associated with increased likelihood of virological failure. | en_US |
dc.description.sponsorship | (Grant numbers R25-TW008102, RO1-AI66922, P30AI042853, and 5U01AI069911). | en_US |
dc.language.iso | en | en_US |
dc.publisher | National institute of health | en_US |
dc.subject | HIV | en_US |
dc.subject | Treatment interruption | en_US |
dc.subject | Political crisis | en_US |
dc.subject | Virological failure | en_US |
dc.subject | Drug resistance | en_US |
dc.title | Antiretroviral treatment interruptions induced by the Kenyan post election crisis are associated with virological failure | en_US |
dc.type | Article | en_US |
Appears in Collections: | School of Medicine |
Files in This Item:
File | Description | Size | Format | |
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B Nathan.pdf | 338.71 kB | Adobe PDF | View/Open |
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