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DC Field | Value | Language |
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dc.contributor.author | Snelgrove, John W. | - |
dc.contributor.author | Alera, Joy Marsha | - |
dc.contributor.author | Foster, Michael C. | - |
dc.contributor.author | Bett, Kipchumba C. N. | - |
dc.contributor.author | Bloomfield, Gerald S. | - |
dc.contributor.author | Silversides, Candice K. | - |
dc.contributor.author | Barasa, Felix A. | - |
dc.contributor.author | Christoffersen-Deb, Astrid | - |
dc.contributor.author | Millar, Heather C. | - |
dc.contributor.author | Thorne, Julie G. | - |
dc.contributor.author | Spitzer, Rachel F. | - |
dc.contributor.author | Vedanthan, Rajesh | - |
dc.contributor.author | Okun, Nanette | - |
dc.date.accessioned | 2022-09-29T07:30:38Z | - |
dc.date.available | 2022-09-29T07:30:38Z | - |
dc.date.issued | 2021-02-09 | - |
dc.identifier.uri | https://doi.org/10.5334/gh.826 | - |
dc.identifier.uri | http://ir.mu.ac.ke:8080/jspui/handle/123456789/6832 | - |
dc.description.abstract | Background: Rheumatic heart disease (RHD) in sub-Saharan Africa contributes to significant cardiac morbidity and mortality, yet prevalence estimates of RHD lesions in pregnancy are lacking. Objectives: Our first aim was to evaluate women using echocardiography to estimate the prev- alence of RHD and other cardiac lesions in low-risk pregnancies. Our second aim was to assess the feasibility of screening echocardiography and its acceptability to patients. Methods: We prospectively recruited 601 pregnant women from a low-risk antenatal clinic at a tertiary care maternity centre in Western Kenya. Women completed a questionnaire about past medical history and cardiac symptoms. They underwent standardized screening echocardiography to evaluate RHD and non-RHD associated cardiac lesions. Our primary out- come was RHD-associated cardiac lesions and our secondary outcome was a composite of any clinically-relevant cardiac lesion or echocardiography finding. We also recorded duration of screening echocardiography and its acceptability among pregnant women in this sample. Results: The point prevalence of RHD-associated cardiac lesions was 5.0/1,000 (95% confidence interval: 1.0–14.5), and the point prevalence of all clinically significant lesions/findings was 21.6/1,000 (11.6–36.7). Mean screening time was seven minutes (SD 1.7, range: 4–17) for women without cardiac abnormalities and 13 minutes (SD 4.6, range: 6–23) for women with abnormal findings. Echocardiography was acceptable to women with 74.2% agreeing to participate. Conclusions: The prevalence of clinically-relevant cardiac lesions was moderately high in a low- risk population of pregnant women in Western Kenya. | en_US |
dc.language.iso | en | en_US |
dc.publisher | PMC | en_US |
dc.subject | Rheumatic heart disease | en_US |
dc.subject | Pregnancy | en_US |
dc.subject | Echocardiography | en_US |
dc.subject | Epidemiology | en_US |
dc.title | Prevalence of rheumatic heart disease and other cardiac conditions in low-risk pregnancies in Kenya: A prospective echocardiography screening study | en_US |
dc.type | Article | en_US |
Appears in Collections: | School of Medicine |
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