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http://ir.mu.ac.ke:8080/jspui/handle/123456789/5665
Title: | Prevalence of hepatitis B virus infection and uptake of hepatitis B vaccine among healthcare workers, Makueni County, Kenya 2017 |
Authors: | Kisangau, EN A Awour, Juma B Odhiambo, D Muasya, T Kiio, SN Too, R Lowther, SA |
Keywords: | prevalence healthcare workers healthcare workers hepatitis B Virus |
Issue Date: | 20-Dec-2019 |
Publisher: | Oxford University Press |
Abstract: | Background Hepatitis B virus (HBV) is a vaccine-preventable infection that can spread in healthcare setting. Data on HBV infections and vaccine in African healthcare workers (HCWs) are limited. We estimated HBV infection prevalence, hepatitis B vaccination status and identified factors associated with vaccination in one Kenyan county. Methods Randomly selected HCWs completed a questionnaire about HBV exposure and self-reported immunization histories, and provided blood for testing of selected HBV biomarkers to assess HBV infection and vaccination status: HBV core antibodies (anti-HBc), HBV surface antigen (HBsAg) and HBV surface antibodies (anti-HBs). Prevalence odds ratios (OR) with 95% confidence intervals (95% CI) were calculated to identify factors associated with vaccination. Results Among 312 HCWs surveyed, median age was 31 years (range: 19–67 years). Of 295 blood samples tested, 13 (4%) were anti-HBc and HBsAg-positive evidencing chronic HBV infection; 139 (47%) had protective anti-HBs levels. Although 249 (80%) HCWs received ≥1 HBV vaccine dose, only 119 (48%) received all three recommended doses. Complete vaccination was more likely among those working in hospitals compared to those working in primary healthcare facilities (OR = 2.5; 95% CI: 1.4–4.3). Conclusion We recommend strengthening county HCW vaccination, and collecting similar data nationally to guide HBV prevention and control. |
URI: | http://ir.mu.ac.ke:8080/jspui/handle/123456789/5665 |
Appears in Collections: | School of Aerospace Sciences |
Files in This Item:
File | Description | Size | Format | |
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R. Too.pdf | 215.84 kB | Adobe PDF | View/Open |
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