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Title: | Validation of a short adherence questionnaire for children living with HIV on antiretroviral therapy in Kenya |
Authors: | Vreeman, Rachel C. E., James Ayaya, Samuel O. Nyandiko, Winstone M. |
Keywords: | Antiretroviral therapy Validation testing |
Issue Date: | Jul-2016 |
Publisher: | Sage |
Abstract: | Background: There are few validated tools to measure adherence for children living with HIV. We identified questionnaire items for caregivers of Kenyan children aged <15 years living with HIV. Methods: Caregiver–child dyads were followed for 6 months. At monthly visits, the child’s HIV provider administered a 10-item questionnaire to the caregiver. Children were given electronic dose monitors (Medication Event Monitoring Systems [MEMS]). Correlation between questionnaire items and dichotomized MEMS adherence (≥90% doses taken versus <90%) was investigated using logistic regression models. Results: In 95 caregiver–child dyads, mean age of children (40% female) was 8.3 years. Items associated with higher odds of MEMS adherence in multivariable analysis included the father giving the child medication, being enrolled in a nutrition program, and the caregiver reporting no difficulties giving the child medication. Conclusion: Providers typically ask about missed doses, but asking about caregiver responsibilities and difficulties in giving the child medication may better detect suboptimal adherence. |
URI: | https://doi.org/10.1177/2325958218820329 http://ir.mu.ac.ke:8080/jspui/handle/123456789/4051 |
Appears in Collections: | School of Medicine |
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