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DC Field | Value | Language |
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dc.contributor.author | Orang’o, Elkanah O. | - |
dc.contributor.author | Omodi, Victor | - |
dc.contributor.author | Itsura, Peter M. | - |
dc.contributor.author | Tonui, Philip K. | - |
dc.contributor.author | Muthoka, Kapten | - |
dc.contributor.author | Kiptoo, Stephen | - |
dc.date.accessioned | 2020-10-19T09:00:39Z | - |
dc.date.available | 2020-10-19T09:00:39Z | - |
dc.date.issued | 2020 | - |
dc.identifier.uri | https://doi.org/10.1002/ijgo.13330 | - |
dc.identifier.uri | http://ir.mu.ac.ke:8080/jspui/handle/123456789/3627 | - |
dc.description.abstract | Objective To assess the baseline types of HPV infection among HIV‐positive and HIV‐negative women in western Kenya undergoing cryotherapy or loop electrosurgical excision procedure (LEEP) for cervical intraepithelial neoplasia. Methods A prospective observational study was conducted of baseline HPV characteristics of women undergoing visual inspection with acetic acid (VIA) and cryotherapy or LEEP. After a positive VIA in HIV‐positive and HIV‐negative women, data on demographics, CD4 count, and use of antiretroviral therapy and a cervical swab were collected. HPV typing was performed using the Roche Linear Array. Results Of 175 participants, 86 (49.1%) were HIV‐positive and had a higher prevalence of low‐risk HPV types (odds ratio [OR] 5.28, P=0.005) compared with HIV‐negative women. The most common high‐risk (HR)‐HPV types in HIV‐positive women were HPV 16 (13.9%) and HPV 18 (11.1%). HIV‐positive women requiring LEEP were more likely to have HR‐HPV types (OR 6.67, P=0.012) and to be infected with multiple HR‐HPV types (OR 7.79, P=0.024) compared to those undergoing cryotherapy. Conclusion HIV‐positive women requiring LEEP versus cryotherapy had a higher prevalence of any HR‐HPV type and multiple HR‐HPV types. There were no such differences in HPV types identified among HIV‐negative women. | en_US |
dc.language.iso | en | en_US |
dc.publisher | International Journal of Gynecology & Obstetrics | en_US |
dc.subject | Cryotherapy procedure | en_US |
dc.subject | Invasive cervical cancer | en_US |
dc.title | Detection of types of HPV among HIV‐infected and HIV‐uninfected Kenyan women undergoing cryotherapy or loop electrosurgical excision procedure | en_US |
dc.type | Article | en_US |
Appears in Collections: | School of Medicine |
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