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DC Field | Value | Language |
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dc.contributor.author | Oyieng'o, Park D | - |
dc.contributor.author | Kisang, G | - |
dc.contributor.author | Sitienei, J. | - |
dc.contributor.author | Diero, L. | - |
dc.date.accessioned | 2020-10-19T07:48:10Z | - |
dc.date.available | 2020-10-19T07:48:10Z | - |
dc.date.issued | 2012-06 | - |
dc.identifier.uri | https://doi.org/10.5588/pha.12.0002 | - |
dc.identifier.uri | http://ir.mu.ac.ke:8080/jspui/handle/123456789/3623 | - |
dc.description.abstract | BACKGROUND: In the light of the 2010 World Health Organization estimation of 650 000 cases of multidrug-resistant tuberculosis (MDR-TB) globally, the need to develop, implement and scale up MDR-TB treatment programs is clear. The need is greatest and urgent in resource-poor countries, such as Kenya, with a high TB burden and an anticipated rise in reported cases of MDR-TB with increasing access to drug susceptibility testing. OBJECTIVES: To describe the set-up of a community-based program, early clinical outcomes, challenges and possible solutions. SETTING: The Moi Teaching and Referral Hospital (Moi Hospital) catchment areas: Western and North Rift Provinces, Kenya. DESIGN: Program description and retrospective chart review. RESULTS: An MDR-TB team established a community-based program with either home-based DOT or local facility-based DOT. Following referral, the team instituted a home visit, identified and hired a DOT worker, trained family and local health care professionals in MDR-TB care and initiated community-based MDR-TB treatment. In the first 24 months, 14 patients were referred, 5 died prior to initiation of treatment and one had extensively drug-resistant TB. Among eight patients who initiated community-based DOT, 87% underwent culture conversion by 6 months, and 75% were cured with no relapse after a median follow-up of 15.5 months. Multiple challenges were experienced, including system delays, stigma and limited funding. CONCLUSION: Despite multiple challenges, our model of an MDR-TB team that establishes a community-based treatment system encircling diagnosed cases of MDR-TB is feasible, with acceptable treatment outcomes. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Ampath | en_US |
dc.subject | resistant tuberculosis | en_US |
dc.subject | community DOTS-Plus | en_US |
dc.title | ommunity based treatment of multidrug resistant tuberculosis: early experience and results from Western Kenya | en_US |
dc.type | Article | en_US |
Appears in Collections: | School of Medicine |
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