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Title: | Human immunodeficiency Virus and leprosy coinfection: challenges in resource limited setups |
Authors: | Siika, Abraham M. Kwobah, Charles M. Kara, Wools Kaloustian K. Gitau, Jane N. |
Keywords: | HIV Resource-Limited Setups |
Issue Date: | 2012 |
Publisher: | Amapth |
Abstract: | Mycobacteria leprae(leprosy) and HIV coinfection are rare in Kenya. This is likely related to the low prevalence (1 per 10,000 of population) of leprosy. Because leprosy is no longer a public health challenge there is generally a low index of suspicion amongst clinicians for its diagnosis. Management of a HIV-1-leprosy-coinfected individual in a resource-constrained setting is challenging. Some of these challenges include difficulties in establishing a diagnosis of leprosy; the high pill burden of cotreatment with both antileprosy and antiretroviral drugs (ARVs); medications’ side effects; drug interactions; scarcity of drug choices for both diseases. This challenge is more profound when managing a patient who requires second-line antiretroviral therapy (ART). We present an adult male patient coinfected with HIV and leprosy, who failed first-line antiretroviral therapy (ART) and required second-line treatment. Due to limited choices in antileprosy drugs available, the patient received monthly rifampicin and daily lopinavir- /ritonavir-based antileprosy and ART regimens, respectively. Six months into his cotreatment, he seemed to have adequate virological control. This case report highlights the challenges of managing such a patien |
URI: | http://ir.mu.ac.ke:8080/jspui/handle/123456789/3513 |
Appears in Collections: | School of Medicine |
Files in This Item:
File | Description | Size | Format | |
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Siika Abraham M..et.alpdf | 524.47 kB | Adobe PDF | View/Open |
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