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http://ir.mu.ac.ke:8080/jspui/handle/123456789/3380
Title: | Symptom screen: diagnostic usefulness in detecting pulmonary tuberculosis in HIV-infected pregnant women in Kenya |
Authors: | Kosgei, R. J. Ndavi, P. M Ong’ech, J. O. Abuya, J. M. Siika, A. M Wools Kaloustian, K. Mabeya, H. Fojo, T. Mwangi, A. Carter, E. J. |
Keywords: | HIV pregnant women pulmonary tuberculosis |
Issue Date: | Oct-2011 |
Publisher: | Ampath |
Abstract: | Objective: To determine the diagnostic usefulness of tu- berculosis (TB) symptom screening to detect active pul- monary TB among human immunodeficiency virus (HIV) infected pregnant women in two PMTCT (prevention of mother-to-child transmission) clinics in western Kenya that are supported by the United States Agency for Inter- national Development–Academic Model Providing Access to Healthcare partnership. Design: Cross-sectional study. Participants were inter- viewed for TB symptoms with a standardized question- naire (cough >2 weeks, fever, night sweats, weight loss or failure to gain weight). Those with cough submitted spu- tum specimens for smear microscopy for acid-fast bacilli and mycobacterial culture. Women at >14 weeks gesta- tion underwent shielded chest radiography (CXR). Results: Of 187 HIV-infected women, 38 (20%) were symptom screen-positive. Of these, 21 had a cough for >2 weeks, but all had negative sputum smears and my- cobacterial cultures. CXRs were performed in 26 symp- tomatic women: three were suggestive of TB (1 miliary, 1 infiltrates and 1 cavitary). Of 149 women with a nega- tive symptom screen, 100 had a CXR and seven had a CXR suggestive of TB (1 cavitary, 2 miliary and 4 infiltrates). Conclusion: This study did not support the utility of iso- lated symptom screening in identification of TB disease in our PMTCT setting. CXR was useful in identification of TB suspects in both symptomatic and asymptomatic women |
URI: | http://ir.mu.ac.ke:8080/jspui/handle/123456789/3380 |
Appears in Collections: | School of Medicine |
Files in This Item:
File | Description | Size | Format | |
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Kosgei R.J..et.al .pdf | 512 kB | Adobe PDF | View/Open |
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