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http://ir.mu.ac.ke:8080/jspui/handle/123456789/3196
Title: | Cardiovascular complications of HIV in endemic countries |
Authors: | Bloomfield, Gerald S. Bogorodskaya, Milana |
Keywords: | Cardiovascular HIV Endemic |
Issue Date: | 2016 |
Publisher: | PMC |
Abstract: | Effective combination antiretroviral therapy (ART) has enabled human immunodeficiency virus (HIV) infection to evolve from a generally fatal condition to a manageable chronic disease. This transition began two decades ago in high-income countries, and has more recently begun in lower income, HIV endemic countries (HIV-ECs). With this transition, has come a concurrent shift in clinical and public health burden from AIDS-related complications and opportunistic infections, to those associated with well-controlled HIV disease, including cardiovascular disease (CVD). In the current treatment era, traditional CVD risk factors and HIV-related factors both contribute to an elevated risk of myocardial infarction, stroke, heart failure, and arrhythmias. In HIV-ECs, the high prevalence of persons living with HIV and growing prevalence of CVD risk factors will contribute to a growing epidemic of HIV-associated CVD. In this review, we discuss the epidemiology and pathophysiology of cardiovascular complications of HIV and the resultant implications for public health efforts in HIV-ECs. |
URI: | http://ir.mu.ac.ke:8080/jspui/handle/123456789/3196 |
Appears in Collections: | School of Medicine |
Files in This Item:
File | Description | Size | Format | |
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Cardiovascular Complications of HIV in Endemic Countries | 314.92 kB | Adobe PDF | View/Open |
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