Please use this identifier to cite or link to this item:
http://ir.mu.ac.ke:8080/jspui/handle/123456789/3040
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lang, T. | - |
dc.contributor.author | Meara, W. P. O | - |
dc.date.accessioned | 2020-06-02T08:09:30Z | - |
dc.date.available | 2020-06-02T08:09:30Z | - |
dc.date.issued | 2009 | - |
dc.identifier.uri | http://ir.mu.ac.ke:8080/jspui/handle/123456789/3040 | - |
dc.description.abstract | A recent working group convened by the World Health Organization recommended that time to first or only episode of clinical malaria should be used to evaluate vaccine efficacy in phase III trials. However, calculating vaccine efficacy based on this endpoint misses important aspects of malaria disease and transmission. Here, we discuss the gaps that this approach leaves in predicting the potential public health impact of a vaccine and the challenges faced by vaccine trial designers. We examine the implications of current vaccine trial design on effectiveness studies and the next generation of malaria vaccines | en_US |
dc.language.iso | en | en_US |
dc.publisher | Ampath | en_US |
dc.subject | Malaria | en_US |
dc.subject | Vaccine | en_US |
dc.subject | Clinical trial | en_US |
dc.subject | Efficacy | en_US |
dc.title | Malaria vaccine trial endpoints - Bridging the gaps between trial design, Public Health and the Next Generation of Vaccines | en_US |
dc.type | Article | en_US |
Appears in Collections: | School of Medicine |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Malaria vaccine trial endpoints – bridging the gaps between trial design, public health and the next generation of vaccines 2009 | 16.3 kB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.