Please use this identifier to cite or link to this item:
http://ir.mu.ac.ke:8080/jspui/handle/123456789/2626
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kimaiyo Sylvester | - |
dc.contributor.author | Sang Edwin | - |
dc.contributor.author | Keter Alfred | - |
dc.contributor.author | Carter E Jane | - |
dc.contributor.author | Bloomfield Gerald S | - |
dc.contributor.author | Hogan Joseph W | - |
dc.contributor.author | Velazquez Eric J | - |
dc.date.accessioned | 2019-02-05T06:17:30Z | - |
dc.date.available | 2019-02-05T06:17:30Z | - |
dc.date.issued | 2011-07-14 | - |
dc.identifier.uri | http://ir.mu.ac.ke:8080/xmlui/handle/123456789/2626 | - |
dc.description.abstract | Background There is increased risk of cardiovascular disease among HIV seropositive individuals. The prevalence of HIV is highest in sub-Saharan Africa; however, HIV-related cardiovascular risk research is largely derived from developed country settings. Herein, we describe the prevalence of hypertension and obesity in a large HIV treatment program in Kenya. Methods We performed a retrospective analysis of the electronic medical records of a large HIV treatment program in Western Kenya between 2006 and 2009. We calculated the prevalence of hypertension and obesity among HIV+ adults as well as utilized multiple logistic regression analyses to examine the relationship between clinical characteristics, HIV-related characteristics, and hypertension. Results Our final sample size was 12,194. The median systolic/diastolic blood pressures were similar for both sexes (male: 110/70 mmHg, female: 110/70 mmHg). The prevalence of hypertension among men and women were 11.2% and 7.4%, respectively. Eleven percent of men and 22.6% of women were overweight/obese (body mass index ≥25 kg/m2). Ordinal logistic regression analyses showed that overweight/obesity was more strongly associated with hypertension among HIV+ men (OR 2.41, 95% CI 1.88–3.09) than a higher successive age category (OR 1.62, 95% CI 1.40–1.87 comparing 16–35, 36–45 and >45 years categories). Among women, higher age category and overweight/obesity were most strongly associated with hypertension (age category: OR 2.21, 95% CI 1.95–2.50, overweight/obesity: OR 1.80, 95% CI 1.50–2.16). Length of time on protease inhibitors was not found to be related to hypertension for men (OR 1.62, 95% CI 0.42–6.20) or women (OR 1.17, 95% CI 0.37–2.65) after adjustment for CD4 count, age and BMI. Conclusion In Western Kenya, there is a high prevalence of hypertension and overweight/obesity among HIV+ patients with differences observed between men and women. The care of HIV+ patients in sub-Saharan Africa should also include both identification and management of associated cardiovascular risk factors. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Journals.plos.org | en_US |
dc.subject | Hypertension | en_US |
dc.subject | Obesity | en_US |
dc.subject | HIV Seropositive | en_US |
dc.title | Hypertension and Obesity as Cardiovascular Risk Factors among HIV Seropositive Patients in Western Kenya | en_US |
dc.type | Article | en_US |
Appears in Collections: | School of Medicine |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Kimaiyo Slyvester 2011 | 178.74 kB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.